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The tag sequence is incorporated into the recombinant protein by means of an expression vector positioned alongside the DNA sequence encoding the protein itself

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While GLP-1 medications like semaglutide and tirzepatide have demonstrated significant weight loss effects, their specific role in lipedema management remains under investigation

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Semaglutide represents a more selective experimental model because it primarily targets the GLP 1 receptor without concurrent GIP receptor or glucagon receptor activity

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